1. Abstract China was very poor for more than a few decades after WWII and was hit by severe famines in the end of the 1950s and the early-60s. Its economy started to make remarkably rapid progress in the 1980s to become nearly equivalent to the other north-east- ern countries, Japan and South Korea, toward […]
1. Abstract The xx-xy gender theory discovered in 1905 became the stake for scientific wisdom as a basis for development of genders. This study was conducted on known case-by-case deep analysis to establish causes and effects. The example case results are presented for different types of aberrations to induce confidence in the readers.
1. Abstract 1.1. Background/Aims: The PAIR (Puncture, Aspiration, Injection of scolicidal agent, and Reaspiration) treatment is used for echinococcosis type 1 (CE1) liver hydatid cysts. The aim of this study is to show the relationship between the cyst diameter and long-term results of PAIR.
1. Abstract 1.1. Background: Capecitabine is an oral prodrug used for the treatment of various cancer diseases. Capecitabine is activated to 5-FU. The most severe adverse effect is “hand-foot syndrome.
Effect of Ambient Temperature on Daily Hospital Admissions for Upper Gastrointestinal Bleeding in Nanchang, China: A Time-Series Analysis
1. Abstract 1.1. Background: Hospital admission for upper gastrointestinal bleeding (UGB) increased in cold months indicate that ambient temperature might be associated with UGB.
Chitinase-3 Like-Protein-1 (YKL-40) Promotes Anorectal Mucosal Melanoma Progression via the PI3K-AKT Signaling Pathway
1. Abstract 1.1. Objective: To investigate whether chitinase-3-like protein-1 (YKL-40) promotes the development of anorectal mucosal melanoma through the PI3K-AKT signaling pathway.
1. Abstract 1.1. Importance: Early identification of patients with Novel Coro- naVirus disease (COVID-19) is an essential tool for delivering proper treatment, discharging safely patients to home and optimiz- ing the use of available resources.
1. Abstract 1.1. Background: Breast cancer is the most prevalence cause of cancer death among women and the fifth largest cause of cancer death globally, treatment of breast cancer include hormonal that can be change to other chemotherapy when the response is poor, Paclitaxel is the one of the most chemotherapy used in this reason […]
Clinical determinants of outcome and respiratory management in COVID-19 mechanically ventilated patients with Acute Respiratory Distress Syndrome: A 15-month prospective observational study in a Greek Intensive Care Unit
1.1. Background: Covid-19 associated acute respiratory distress syndrome (CARDS) and prolonged mechanical ventilation im poses a major burden on affected critically ill individuals, in light of high mortality. We aimed to identify possible risk factors for mortality among the three categories of ARDS severity according to Berlin definition and to examine the effect of time on patients’ oxygenation and respiratory mechanics. 1.2. Methods: We prospectively investigated the clinical charac teristics and outcome of 196 consecutive mechanically ventilated patients with CARDS, along with oxygenation and respiratory me chanics, on ICU days 1, 3 and 7. 1.3. Results: ICU mortality accounted for 63.3%. Non-survivors were significantly older and presented higher disease severity on ICU admission and higher incidence of chronic obstructive pulmo nary disease (COPD), neurologic disease and immunosuppression. PaO2/FiO2 was significantly higher in the survivors group at all time points, whereas significant increase over time (day 7 vs day 1) was observed only in survivors group. Static respiratory system compliance was higher and driving pressure was lower in survi vors compared to non survivors, on days 3 and 7. Regarding the non-survivors group, oxygenation remained unchanged through different time points, while compliance reduced significantly and plateau and driving pressures increased through evolution of time. Mild, moderate and severe CARDS was reported in 16 (8.2%), 88 (44.9%) and 92 (46.9%) patients respectively. Incidence of obe sity was higher in severe CARDS. PEEP levels and plateau pres sures were higher in the severe CARDS, while respiratory system compliance and driving pressure did not differ among the CARDS categories. 1.4. Conclusions: In our case series, ICU mortality was high and increased accordingly to CARDS severity. Mortality risk factors included older age, COPD, neurological disorders and immuno suppression. Body mass index was significantly increased across CARDS severity. Trajectories of hypoxemia and respiratory me chanics were also associated with outcome
Proximal humerus fractures account for 5-6% of all adult frac tures. There is increasing recognition given in regard to managing these fractures in the setting of elderly, low-energy falls as these events are contributing to the global impact of direct and indirect costs of osteoporosis and fragility fractures.